High Desert follows Peggy Newman, a former addict who decides to make a new start after the death of her beloved mother, with whom she lived in the small desert town of Yucca Valley, California. Faced with a crossroads in her life, she impulsively decides to become a private investigator, hoping to find purpose and redemption in a place where secrets are buried as deep as the desert sand. As Peggy navigates her new career, she finds herself entangled in a web of eccentric characters, local crime, and her own unresolved past. Her journey is marked by chaotic decision-making, a desperate need for connection, and the struggle to maintain her sobriety while dealing with the bizarre and often dangerous situations that come with her new profession.