Set during the late Qing Dynasty, the series follows Du Zhong, a highly skilled imperial physician who is summoned to the Forbidden City to serve Emperor Guangxu. As he navigates the treacherous political landscape of the imperial court, he finds himself caught between the Emperor's reformist ambitions and the iron-fisted control of Empress Dowager Cixi. Alongside his professional duties, Du Zhong forms an unlikely alliance with the sharp-witted midwife Fu Ling. Together, they uncover deep-seated conspiracies and medical mysteries that threaten the stability of the throne. As the dynasty begins to crumble, Du Zhong must decide where his true loyalties lie—with the crumbling monarchy or the people he swore to protect.