Two Guys, a Girl and a Pizza Place

Set in Boston, the series follows the intertwined lives of two roommates, a cynical medical student and a carefree slacker, and their longtime female friend as they navigate their twenties. The main hub of their early interactions is Beacon Street Pizza, a local pizza parlor where they frequently hang out and work alongside eccentric colleagues. Over the course of the run—later shortened to simply 'Two Guys and a Girl'—the characters mature, transition through various careers in medicine, fire-fighting, and corporate life, and deal with shifting romantic entanglements and existential quarter-life crises.